ABSTRACT
BACKGROUND/AIMS: We investigated the incidence and clinical characteristics of renal cell carcinoma (RCC) in the native kidney of renal transplant recipients. METHODS: Between 1991 and 2010, 1,425 patients underwent kidney transplantation at our institution. We retrospectively evaluated the clinical features and outcomes in renal transplant patients with RCC in the native kidney after renal transplantation. RESULTS: The patients included three males and two females with a mean age of 63 years (range, 52 to 74). The incidence of RCC was 0.35%. The median interval between renal transplantation and RCC occurrence was 16.2 years (range, 9 to 20). All of our patients with RCC had developed renal cysts either before (n = 3) or after (n = 2) renal transplantation. The mean duration of dialysis was 12 months (range, 2 to 39). Of the five patients, four underwent dialysis treatment for less than 8 months. All the RCCs were low grade at the time of diagnosis. Four patients underwent radical nephrectomy, and one patient refused the operation. The four patients who underwent radical nephrectomy showed no evidence of local recurrence or distant metastasis during the median follow-up of 2.9 years. However, the patient who did not undergo surgery developed spinal metastasis from the RCC 6 years later. CONCLUSIONS: This study suggests that the follow-up period is an important factor for the development of RCC in renal transplant recipients, and more vigorous screening with a longer follow-up period is required in renal transplant recipients.
Subject(s)
Aged , Female , Humans , Male , Middle Aged , Carcinoma, Renal Cell/epidemiology , Incidence , Kidney Neoplasms/epidemiology , Kidney Transplantation , Postoperative Complications/epidemiology , Republic of Korea/epidemiology , Retrospective StudiesABSTRACT
No abstract available.
Subject(s)
Humans , Male , Middle Aged , Antiviral Agents/therapeutic use , Biopsy , Chest Pain/diagnosis , Cytomegalovirus/isolation & purification , Cytomegalovirus Infections/diagnosis , Esophagitis/diagnosis , Esophagoscopy , Ganciclovir/therapeutic use , Kidney Transplantation/adverse effects , Opportunistic Infections/diagnosis , Treatment OutcomeABSTRACT
Hemolytic uremic syndrome (HUS) is a rare disorder characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. HUS arises from a wide spectrum of conditions, and chemotherapeutic agents have been reported to be associated with HUS, including Mitomycin, Cisplatin, Bleomycin, and Gemcitabine. A 76-year-old man treated with Gemcitabine due to non-small cell lung cancer developed clinical and laboratory findings compatible with HUS. Gemcitabine was ceased and hemodialysis and plasma exchange were utilized and he recovered. A high level of suspicion for HUS is necessary when cancer patients are treated with Gemcitabine, and prompt recognition and treatment are also essential.
Subject(s)
Aged , Humans , Acute Kidney Injury , Anemia, Hemolytic , Bleomycin , Carcinoma, Non-Small-Cell Lung , Cisplatin , Deoxycytidine , Hemolytic-Uremic Syndrome , Lung , Lung Neoplasms , Mitomycin , Plasma Exchange , Renal Dialysis , ThrombocytopeniaABSTRACT
Rectal foreign bodies are rare clinical problem in South Korea. Although many foreign bodies can be extracted safely using endoscopic procedures, some patients require surgery. Here we describe the case of a 35-year-old male who presented with a rectosigmoid foreign body, a large carrot measuring 28x7 cm. Sigmoidoscopy revealed a carrot in the upper rectum extending to the sigmoid colon. Endoscopic removal failed. The surgeon unsuccessfully attempted to extract the carrot using various tools without spinal anesthesia. During the extraction attempt, the patient complained of sudden abdominal pain, and a simple x-ray revealed pneumoperitoneum. An emergency colotomy and removal of the foreign body was performed, followed by primary repair of the perforation and a colostomy. Three months later, the colostomy was repaired.
Subject(s)
Adult , Humans , Male , Abdominal Pain , Anesthesia, Spinal , Colon, Sigmoid , Colostomy , Daucus carota , Emergencies , Endoscopy, Gastrointestinal , Foreign Bodies , Intestinal Perforation , Pneumoperitoneum , Rectum , Republic of Korea , SigmoidoscopyABSTRACT
Left ventricle-coronary sinus fistula and left ventricular pseudoaneurysm are unusual and frightening complications after mitral valve replacement. A 27-year-old female patient underwent mitral valve replacement 5 years previously and trans-thoracic echocardiography showed an outpouching lesion at the atrioventricular groove. It was difficult to differentiate whether the lesion was a left ventricle-coronary sinus fistula or a left ventricular pseudoaneurysm by two-dimensional echocardiography. Cardiac computed tomography confirmed a left ventricular pseudoaneurysm compressing the coronary sinus.